A T cell redirection platform for co-targeting dual antigens on solid tumors
In order to direct T cells to specific features of solid cancer cells, we engineered a bispecific antibody format, named Dual Antigen T cell Engager (DATE), by fusing a single-chain variable fragment targeting CD3 to a tumor-targeting antigen-binding fragment. In this format, multiple novel paratope...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Journal Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2021-01-01
|
| Series: | mAbs |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/19420862.2021.1933690 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|