Deciphering cross-species reactivity of LAMP-1 antibodies using deep mutational epitope mapping and AlphaFold
ABSTRACTDelineating the precise regions on an antigen that are targeted by antibodies has become a key step for the development of antibody therapeutics. X-ray crystallography and cryogenic electron microscopy are considered the gold standard for providing precise information about these binding sit...
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Main Authors: | , , , , , |
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Format: | Journal Article |
Language: | English |
Published: |
Taylor & Francis Group
2023-12-01
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Series: | mAbs |
Subjects: | |
Online Access: | https://www.tandfonline.com/doi/10.1080/19420862.2023.2175311 |
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