CDR loop interactions can determine heavy and light chain pairing preferences in bispecific antibodies
As the current biotherapeutic market is dominated by antibodies, the design of different antibody formats, like bispecific antibodies, is critical to the advancement of the field. In contrast to monovalent antibodies, which consist of two identical antigen-binding sites, bispecific antibodies can ta...
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| Main Authors: | , , , , , |
|---|---|
| Format: | Journal Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2022-12-01
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| Series: | mAbs |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/19420862.2021.2024118 |
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