Characterization and internalization of small extracellular vesicles released by human primary macrophages derived from circulating monocytes. oleh Luis A Arteaga-Blanco, Andrés Mojoli, Robson Q Monteiro, Vanessa Sandim, Rubem F S Menna-Barreto, Filipe Santos Pereira-Dutra, Patrícia T Bozza, Rafael de Oliveira Resende, Dumith Chequer Bou-Habib

"…To date, there are no published methodological works showing step-by-step the isolation, characterization and internalization of small EVs secreted by human primary macrophages derived from circulating monocytes (MDM-derived sEVs). …"
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A Symbolic Encapsulation Point as Tool for 5G Wideband Channel Cross-Layer Modeling oleh Nenad Stefanovic, Marija Blagojevic, Ivan Pokrajac, Marian Greconici, Yigang Cen, Vladimir Mladenovic

"…Using our deterministic channel model for selected scenarios and comparing it with stochastic models, we show steps towards higherlevel finite state Markov chain (FSMC) modeling, where mentioned QoS parameters become more feasible, placing symbolic encapsulation at the center of cross-layer design. …"
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Dynamics across the structural transitions at elevated temperatures in Na0.7CoO2 oleh Juranyi Fanni, Månsson Martin, Gavilano Jorge L., Mena Mattia, Pomjakushina Ekaterina, Medarde Marisa, Sugiyama Jun, Kamazawa Kazuya, Batlogg Bertram, Ott Hans R., Seydel Tilo

"…The temperature dependence of both the elastic and the inelastic intensities show steps at TA ≈ 290 K and TB ≈ 400 K. At TA the step is shown to be connected to low energy phonons, while at TB the Na ion diffusion suddenly gets fast enough, and the characteristic signal of quasielastic scattering appears. …"
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Development and Evaluation of a Single Dye Duplex Droplet Digital PCR Assay for the Rapid Detection and Quantification of <i>Mycobacterium tuberculosis</i> oleh Raphael Nyaruaba, Jin Xiong, Caroline Mwaliko, Nuo Wang, Belindah J. Kibii, Junping Yu, Hongping Wei

"…The ddPCR assay specificity and sensitivity are both 100% when compared to qPCR. This work shows steps toward the detection and quantification of two targets in a single channel, enabling higher multiplexing to include more targets in future works.…"
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Relationship between dairy cows' hind leg activity and vacuum records during milking oleh D. Meyer, A. Haeussermann, E. Hartung

"…Cows showing kickings had a higher degree of teat-end hyperkeratosis than those showing steppings. The degree of teat-end hyperkeratosis was related to the milking duration.…"
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Molecular Dynamics Simulation of Nanoscale Elastic Properties of Hydrated Na-, Cs-, and Ca-Montmorillonite oleh Lianfei Kuang, Qiyin Zhu, Xiangyu Shang, Xiaodong Zhao

"…The variation of basal spacing of MMT shows step characteristics in the initial crystalline swelling stage followed by an approximately linear change in the subsequent osmotic swelling stage as the increasing of interlayer water content. …"
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Amyloid biomarkers as predictors of conversion from mild cognitive impairment to Alzheimer’s dementia: a comparison of methods oleh Arnd Sörensen, Ganna Blazhenets, Florian Schiller, Philipp Tobias Meyer, Lars Frings, for the Alzheimer Disease Neuroimaging Initiative

"…Prediction accuracies (Harrell’s c) showed step-wise significant increases from Cox-SUVR (c = 0.71; HR = 1.84 per Z-score increase), composite SUVR (c = 0.73; HR = 2.18), CSF Aβ42/Aβ40 (c = 0.75; HR = 3.89) to PES (c = 0.77; HR = 2.71). …"
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Real-world treatment trajectories of adults with newly diagnosed asthma or COPD oleh Daniel Prieto-Alhambra, Talita Duarte-Salles, Edward Burn, Rae Woong Park, Jan A Kors, Carlen Reyes, Jerry A Krishnan, Peter R Rijnbeek, Guy G Brusselle, Aniek F Markus, Markus Haug, Chungsoo Kim, Raivo Kolde, Youngsoo Lee, Hae-Sim Park, Katia MC Verhamme

"…The treatment trajectories showed step-up as well as step-down in treatments.Conclusion Real-world data from claims and EHRs indicate that first-line treatments of asthma and COPD vary widely across countries. …"
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Digital CBT-I versus stepped-care CBT-I to prevent depression one year later oleh P. Cheng, D. Kalmbach, C. Sagong, C. Fellman-Couture, C. Drake

"…Those who did not remit following step-1 dCBT-I showed step-2 insomnia remission rates of 75% following fCBT-I compared to 38% following the step 2 control. …"
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Outcome related to impact on daily living: preliminary validation of the ORIDL instrument oleh Harrison Tansy, Bikker Annemieke P, Mercer Stewart W, Reilly David

"…These improvements were not significantly correlated with changes in serial measures of the EQOL between baseline and 12 months, but were correlated with the EQOL transitions measure. Study 2 showed step-wise improvements in ORIDL scores between 3 and 33 months, which were only weakly associated with similar changes in SF-12 scores. …"
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Groundwater uptake of forest and agricultural land covers in regions of recharge and discharge oleh Móricz N, Tóth T, Balog K, Szabó A, Rasztovits E, Gribovszki Z

"…In the recharge zone the water table under the black locust plantation showed step-like changes referring to the lack of groundwater supply. …"
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Effect of weaning on milking behaviour and temperament of Murrah buffaloes oleh P K BHARTI, TRIVENI DUTT, B H M PATEL, H O PANDEY, MUKESH SINGH, G K GAUR, REENA KAMAL, K K VERMA

"…The percent of dams showing stepping behaviour in Gr 1, Gr 2 and Gr 3 was 20.23, 27.57 and 44.11, respectively, and the corresponding value for kicking behaviour was 2.61, 10.60 and 13.39, respectively. …"
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Effect of hematoma puncture and catheter drainage on perihematomal cerebral hemodynamics evaluated by CT perfusion imaging in intracerebral hemorrhage oleh Hong DENG, Hai-han YU, Ye ZHANG, Ping ZHANG, Chao PAN, Zhong-yuan ZHANG, Zhou-ping TANG

"…There was no significant difference on CBF, CBV, MTT and TTP in remote cortex between hematoma side and enantiomorphic contralateral side (P > 0.05, for all). 2) The perfusion parameters showed stepped change from central hematoma to remote cortex: CBF and CBV showed a gradual increase (P < 0.05, for all), and MTT showed a gradual decrease from central hematoma to remote cortex of hematoma side (P < 0.05, for all), while TTP showed no significant difference (P > 0.05). …"
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Practical aspects of using Witepsol H15 in pharmaceutical compounding oleh Aldona Maciejewska, Krzysztof Niwiński, Kamil Kornaus, Paweł Rutkowski

"…An analysis of the behavior during cooling of Witepsol H15 heated to different temperatures, was carried out and it was found that the overheated base shows stepped thermal changes profile while solidifying. …"
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Heparin versus citrate anticoagulation for continuous renal replacement therapy in intensive care: the RRAM observational study oleh Doug W Gould, James Doidge, M Zia Sadique, Mark Borthwick, Robert Hatch, Fergus J Caskey, Lui Forni, Robert F Lawrence, Clare MacEwen, Marlies Ostermann, Paul R Mouncey, David A Harrison, Kathryn M Rowan, J Duncan Young, Peter J Watkinson

"…Secondary outcomes showed step increases in days of renal support (difference in means 0.53 days, 95% confidence interval 0.28 to 0.79 days), advanced cardiovascular support (difference in means 0.23 days, 95% confidence interval 0.09 to 0.38 days) and advanced respiratory support (difference in means, 0.53 days, 95% CI 0.03 to 1.03 days) with a trend toward fewer bleeding episodes (odds ratio 0.90, 95% confidence interval 0.76 to 1.06) with transition to regional citrate anticoagulation. …"
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The Nature of Parrot and Its Rhetorical Reflections in Persian Poetry oleh Fatemeh Mehri

"…One of our goals is to show these origins and document them with literary evidence. Showing step by step how a natural feature in a parrot brings the poet to create complex images helps to solve poetic problems and understand the intricate imagery of poets.These are our two main questions: How does scrutinizing the nature of parrots help the researcher to better figure out the images and rhetorical associations in which the parrot plays a role? …"
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