Hasil Pencarian - "FHM"

  1. 181

    Overexpressed NaV1.7 Channels Confer Hyperexcitability to in vitro Trigeminal Sensory Neurons of CaV2.1 Mutant Hemiplegic Migraine Mice oleh Riffat Mehboob, Riffat Mehboob, Anna Marchenkova, Arn M. J. M. van den Maagdenberg, Arn M. J. M. van den Maagdenberg, Andrea Nistri

    Diterbitkan 2021-05-01
    "…Trigeminal sensory neurons of transgenic knock-in (KI) mice expressing the R192Q missense mutation in the α1A subunit of neuronal voltage-gated CaV2.1 Ca2+ channels, which leads to familial hemiplegic migraine type 1 (FHM1) in patients, exhibit a hyperexcitability phenotype. …"
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  5. 185

    Largemouth Bass Virus Infection Induced Non-Apoptotic Cell Death in MsF Cells oleh Jiahui Yang, Weihua Xu, Wenji Wang, Zanbin Pan, Qiwei Qin, Xiaohong Huang, Youhua Huang

    Diterbitkan 2022-07-01
    "…In addition, the disruption of the mitochondrial membrane potential (ΔΨm) and reactive oxygen species (ROS) generation were detected in both LMBV-infected MsF cells and fathead minnow (FHM) cells. Combined with our previous study, we propose that cell death induced by LMBV infection was cell type dependent. …"
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  6. 186

    Two distinct phenotypes, hemiplegic migraine and episodic Ataxia type 2, caused by a novel common CACNA1A variant oleh Rosaria Nardello, Giorgia Plicato, Giuseppe Donato Mangano, Elena Gennaro, Salvatore Mangano, Filippo Brighina, Vincenzo Raieli, Antonina Fontana

    Diterbitkan 2020-04-01
    "…Mutations in the CACNA1A gene were identified as responsible for at least three autosomal dominant disorders: FHM1 (Familial Hemiplegic Migraine), EA2 (Episodic Ataxia type 2), and SCA6 (Spinocerebellar Ataxia type 6). …"
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  7. 187

    Comparison of Plant Health Aspect In Green Open Spaces of Alun-Alun Kebumen and Alun-Alun Karanganyar, Kebumen, Central Java oleh Herfiana Anggun Mustika Dewi, Nizar Nasrullah, Bambang Sulistyantara

    Diterbitkan 2024-01-01
    "…This plant damage research have been conducted using the FHM (Forest Health Monitoring) method and the USDA Forest Service damage index. …"
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  8. 188

    New CACNA1A deletions are associated to migraine phenotypes oleh G. S. Grieco, S. Gagliardi, I. Ricca, O. Pansarasa, M. Neri, F. Gualandi, G. Nappi, A. Ferlini, C. Cereda

    Diterbitkan 2018-08-01
    "…Abstract Background Familial hemiplegic migraine type 1 (FHM1) is a form of migraine with aura caused by heterozygous mutations in 4 genes: CACNA1A, ATP1A2, SNC1A and PRRT2, but further heterogeneity is expected. …"
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  9. 189
  10. 190

    Herpes zoster in Germany: Quantifying the burden of disease oleh Reinhold Thomas, Rieck Thorsten, Siedler Anette, Ultsch Bernhard, Krause Gérard, Wichmann Ole

    Diterbitkan 2011-06-01
    "…For the same time period annual number of HZ-inpatients and HZ-associated deaths were identified by using the Federal Health Monitoring System (FHM). PHN-incidence and loss of quality-adjusted life years (QALYs) caused by HZ were calculated by multiplying number of identified HZ-patients with upper and lower limit estimates for proportion of HZ-cases developing PHN and HZ-related QALY, respectively.…"
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  11. 191
  12. 192

    De novo exonic duplication of ATP1A2 in Italian patient with hemiplegic migraine: a case report oleh Stella Gagliardi, Gaetano Salvatore Grieco, Francesca Gualandi, Luisa Maria Caniatti, Elisabetta Groppo, Marialuisa Valente, Giuseppe Nappi, Marcella Neri, Cristina Cereda

    Diterbitkan 2017-06-01
    "…Mutations in three different genes, two ion-channel genes and one encoding an ATP exchanger, CACNA1A, ATP1A2 and SCN1A are all responsible for the FHM phenotype, thus indicating a genetic heterogeneity for this disorder. …"
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  13. 193

    Genetic and Pathogenic Characterization of an Iridovirus from the Cultured Largemouth Bass <i>Micropterus salmoides</i> oleh Yi-Fan Zhang, Ying Li, Peng-Tian Li, Jing Jiang, Wei-Hang Zeng, Kun Ye, Yi-Lei Wang, Peng-Fei Zou

    Diterbitkan 2024-08-01
    "…In the present study, a virus strain named LMBV-GDSD was isolated from cultured largemouth bass and was successfully proliferated in FHM and EPC cells, with numerous viral particles observed in the infected cells under transmission electron microscopy analysis. …"
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  14. 194

    A comprehensive exploration of astrocytes in migraine: a bibliometric and visual analysis oleh Shijie Wei, Tianqi Du, Lili Zhang, Xuhao Li, Zhe Wang, Yike Ning, Yu Tang, Xinyu Wu, Jing Han

    Diterbitkan 2024-06-01
    "…Conclusions Future investigators may continue to focus on migraines with aura, familial hemiplegic migraine (FHM), and the crucial calcitonin gene-related peptide (CGRP) system. …"
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  15. 195

    A novel heterozygous ATP1A2 pathogenic variant in a Chinese child with MELAS‐like alternating hemiplegia oleh Xin Zhang, Shiyan Qiu, Li Yang, Yufen Li, Liyun Xu, Na Xu, Changrui Mi, Menglin Li

    Diterbitkan 2023-05-01
    "…Abstract Background Pathogenic variants of ATP1A2 (OMIM ID: 182340) are usually associated with familial hemiplegic migraine type 2 (FHM‐2), alternating hemiplegia of childhood (AHC), early infantile epileptic encephalopathy (EIEE), transient cytotoxic edema, and so on. …"
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  16. 196

    Transferrin Mediated NCC Killing Activity through NCCRP-1 in Nile Tilapia (<i>Oreochromis niloticus</i>) oleh Yu Huang, Zhengsi Chen, Ruitao Xie, Pei Wang, Zhiqiang Zhang, Jia Cai, Bei Wang, Jichang Jian

    Diterbitkan 2022-09-01
    "…In vitro experiments showed that rOn-TF could up-regulate the expression of killing effector molecule of NCC by On-NCCRP-1, and rOn-TF-activated NCCs showed a significantly improved ability to kill FHM cells, indicating that rOn-TF could regulate the NCC signaling pathway through NCC receptor molecule On-NCCRP-1. …"
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  17. 197

    Hypercontractile Cardiac Phenotype in Mice with Migraine-Associated Mutation in the Na<sup>+</sup>,K<sup>+</sup>-ATPase α<sub>2</sub>-Isoform oleh Rajkumar Rajanathan, Clàudia Vilaseca i Riera, Tina Myhre Pedersen, Christian Staehr, Elena V. Bouzinova, Jens Randel Nyengaard, Morten B. Thomsen, Hans Erik Bøtker, Vladimir V. Matchkov

    Diterbitkan 2023-04-01
    "…Mice heterozygous for the familial hemiplegic migraine type 2 (FHM2) associated mutation in the α<sub>2</sub>-isoform (G301R; α<sub>2</sub><sup>+/G301R</sup> mice) have decreased expression of cardiac α<sub>2</sub>-isoform but elevated expression of the α<sub>1</sub>-isoform. …"
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