Single-cell profiling defines the prognostic benefit of CD39high tissue resident memory CD8+ T cells in luminal-like breast cancer
oleh: Agnese Losurdo, Caterina Scirgolea, Giorgia Alvisi, Jolanda Brummelman, Valentina Errico, Luca Di Tommaso, Karolina Pilipow, Federico Simone Colombo, Bethania Fernandes, Clelia Peano, Alberto Testori, Corrado Tinterri, Massimo Roncalli, Armando Santoro, Emilia Maria Cristina Mazza, Enrico Lugli
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-09-01 |
Deskripsi
Losurdo et al analyze breast cancer-infiltrating T cells by single-cell technologies . The find that the extent of infiltration of a small subset of tissue-resident memory CD8+ T cells identify patients with improved survival, highlighting the importance of the specific T cell immune microenvironment.