Engineered amphiphilic peptides enable delivery of proteins and CRISPR-associated nucleases to airway epithelia
oleh: Sateesh Krishnamurthy, Christine Wohlford-Lenane, Suhas Kandimalla, Gilles Sartre, David K. Meyerholz, Vanessa Théberge, Stéphanie Hallée, Anne-Marie Duperré, Thomas Del’Guidice, Jean-Pascal Lepetit-Stoffaes, Xavier Barbeau, David Guay, Paul B. McCray
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2019-10-01 |
Deskripsi
Delivering biological cargo to airway epithelial cells is very challenging. Here, the authors use engineered amphiphilic peptides to shuttle proteins and CRISPR RNPs into airway cells in vivo.