Accumulation of formaldehyde causes motor deficits in an in vivo model of hindlimb unloading
oleh: Dandan Yao, Qingyuan He, Shangyin Bai, Hang Zhao, Jun Yang, Dehua Cui, Yan Yu, Xuechao Fei, Yufei Mei, Ye Cheng, Shi Yan, Nayan Huang, Yalan Di, Xianjie Cai, Rui Wang, Yajuan Gao, Fangrao Cheng, Shengjie Zhao, Xu Yang, Xiang Cai, Hongbin Han, Jihui Lyu, Zhiqian Tong
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-08-01 |
Deskripsi
Dandan Yao et al. demonstrated that accumulation of formaldehyde in the cerebellum and skeletal muscle contributed toward motor deficits in a mouse model of hindlimb unloading. Their results collectively suggest that scavenging formaldehyde may be a useful treatment to limit motor dysfunction following limb offloading conditions.