3D imaging of human organs with micrometer resolution - applied to the endocrine pancreas

oleh: Max Hahn, Christoffer Nord, Maria Eriksson, Federico Morini, Tomas Alanentalo, Olle Korsgren, Ulf Ahlgren

Format: Article
Diterbitkan: Nature Portfolio 2021-09-01

Deskripsi

Hahn et al. present a method to visualize the endocrine human pancreas in 3D and calculate volumetric data. Using immunolabeling to visualize targets of interest and in reconstructing large tissue parts from imaged cm3-sized tissue blocks, they use their method to reveal previously unknown morphological differences in the endocrine pancreas affected with type 2 diabetes.