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Clinical significance of reopening anterior chamber angle for severe acute angle-closure glaucoma
oleh: Jun-Hong Zhao, Jian-Qiang Guo, Hua Tian, Qi Gou, Xiao-Dong Wang, Pei-Lin Lyv
Format: | Article |
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Diterbitkan: | Press of International Journal of Ophthalmology (IJO PRESS) 2018-07-01 |
Deskripsi
AIM: To explore whether the drainage angle could be reopened by surgery in patients with severe acute angle-closure glaucoma at “the greatest degree” of angle closure, and to study the treatment methods, such as double-paracentesis, phacoemulsification combined with goniosychialysis, and the effectiveness. <p>METHODS: Retrospective observational case series. From November 2008, to November 2015, there were 33 patients with severe acute angle-closure glaucoma and 360° angle closure. Drug treatment showed no effect on them, so initial double-paracentesis(anterior chamber paracentesis combined with vitreous paracentesis)was applied. Then, either phacoemulsification combined with goniosychialysis or trabeculectomy surgery was performed after 7-14d, which was chosen based on the result of gonioscope during the surgery. The intraocular pressure, angle changes, and complications were observed. The follow-up period was 6mo to 3a. <p>RESULTS: Of 33 participants enrolled, 32 had normal intraocular pressure after “double-paracentesis”(2 had normal intraocular pressure after laser peripheral iridotomy). The mean intraocular pressure was significantly reduced from 53.4±10.7mmHg to 16.9±13.2mmHg(<i>t</i>=9.21,<i>P</i><0.001)by applying “double-paracentesis”, and 1 still had higher intraocular pressure. The mean intraocular pressure(16.7±4.8mmHg)was 0.2mmHg lower after phacoemulsification than after “double-paracentesis” while there was no significant difference(<i>t</i>=0.38,<i>P</i>>0.05). One patient had abnormal intraocular pressure until 30d after phacoemulsification. Every participant had 360° angle closed before “double-paracentesis”, 32 patients had opened angle(mean 131.8°±111.3°)after “double-paracentesis” and mean(228.6°±108.3°)during phacoemulsification, and mean(234.6°±107.2°)at 3mo after phacoemulsification. There was a significant difference between the post-paracentesis and intraoperative values(<i>t</i>=4.52, <i>P</i><0.001). There was no difference between the intraoperative and postoperative values(<i>t</i>=0.46, <i>P</i>>0.05). No patients had serious adverse events. <p>CONCLUSION: For the “maximum degree” angle closure of severe acute angle-closure glaucoma, “double-paracentesis” combined with phacoemulsification can be chosen to open the angle gradually, and reduce intraocular pressure in vast majority of patients.