Cooperative assembly of p97 complexes involved in replication termination

oleh: Olga V. Kochenova, Sirisha Mukkavalli, Malavika Raman, Johannes C. Walter

Format: Article
Diterbitkan: Nature Portfolio 2022-11-01

Deskripsi

This study describes how p97Ufd1-Npl4 and the UBA-UBX protein Ubxn7 disassemble vertebrate replisomes during replication termination, and it provides novel insights into how p97 complexes assemble with UBA-UBX proteins on ubiquitylated substrates