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Abstract Cardiac lymphoma is extremely rare in patients with normal immune function and difficult to identify through routine examinations in patients with atypical clinical manifestations, making early diagnosis very difficult. We reported a 71‐year‐old male patient who was repeatedly diagnosed of pulmonary infection, suspected lung tumour, and Kimura disease in other hospital due to cough, expectoration, and dyspnoea. Later on, the patient visited our hospital due to heart failure and epistaxis. Transthoracic echocardiogram confirmed the presence of a space‐occupying lesion in the right heart, cardiac magnetic resonance imaging preliminarily determined the nature of this lesion, finally, 18F‐fluorodeoxyglucose positron‐emission tomography/computed tomography, and nasal mass biopsy confirmed the diagnosis of cardiac malignant lymphoma, and the pathological type was diffuse large B‐cell lymphoma.