Demonstration of targeted crossovers in hybrid maize using CRISPR technology
oleh: Andrei Kouranov, Charles Armstrong, Ashok Shrawat, Vladimir Sidorov, Scott Huesgen, Bryce Lemke, Timothy Boyle, Michelle Gasper, Richard Lawrence, Samuel Yang
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-01-01 |
Deskripsi
Kouranov et al. demonstrate Cas12a-mediated targeted chromosomal crossover (CO) in transgenic hybrid maize plants and produce heritable crossover in F1 plants when Cas12a transgene is segregated away. The authors also report that the frequency of LbCas12a-mediated CO is higher than control natural CO in the same intervals in the progeny of 4 different events.