Effectiveness of Pneumococcal Polysaccharide Vaccine for Preschool-Age Children with Chronic Disease

oleh: Anthony E. Fiore, Orin S. Levine, John A. Elliott, Richard R. Facklam, Jay C. Butler

Format: Article
Diterbitkan: Centers for Disease Control and Prevention 1999-12-01

Deskripsi

To estimate the effectiveness of pneumococcal polysaccharide vaccine, we serotyped isolates submitted to the Pneumococcal Sentinel Surveillance System from 1984 to 1996 from 48 vaccinated and 125 unvaccinated children 2 to 5 years of age. Effectiveness against invasive disease caused by serotypes included in the vaccine was 63%. Effectiveness against serotypes in the polysaccharide vaccine but not in a proposed seven-valent protein conjugate vaccine was 94%.