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In the title compound, C28H26Cl2N4O4S, the dihedral angles between the two chlorophenyl rings and the two oxadiazol rings are 10.51 (4)° and 13.55 (3)°, respectively. The thiophene ring is oriented at dihedral angles of 5.59 (4)°, 8.33 (4)° and 4.41 (4)°, 11.05 (3)°, respectively, with respect to the two oxadiazol and the two chlorophenyl rings. The intramolecular C—H...O hydrogen bond results in the formation of a five-membered ring. In the crystal structure, π–π contacts between the oxadiazol rings, the chlorophenyl rings and the chlorophenyl and oxadiazol rings [centroid–centroid distances = 3.428 (3) Å, 3.750 (3) Å and 3.768 (3) Å, respectively] are present.