Mammalian brain glycoproteins exhibit diminished glycan complexity compared to other tissues

oleh: Sarah E. Williams, Maxence Noel, Sylvain Lehoux, Murat Cetinbas, Ramnik J. Xavier, Ruslan I. Sadreyev, Edward M. Scolnick, Jordan W. Smoller, Richard D. Cummings, Robert G. Mealer

Format: Article
Diterbitkan: Nature Portfolio 2022-01-01

Deskripsi

Protein glycosylation is critical in brain development and disease. Here, the authors characterize brain glycans in detail, showing that they are simpler and more homogenous than glycans from other tissues and providing a basis for future studies of brain glycosylation.