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Comparison of anthropometric and metabolic parameters between normal and deficient vitamin D polycystic ovarian syndrome women
oleh: Anupama Bahadur, Rajlaxmi Mundhra, Jyotshna Kashibhatla, Neha Verma, Rashmi Rajput, Yogesh Bahurupi
Format: | Article |
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Diterbitkan: | Wolters Kluwer Medknow Publications 2021-01-01 |
Deskripsi
Objective: To compare the anthropometric and metabolic parameters between normal and deficient Vitamin D PCOS women. Materials and Methods: All women with polycystic ovary syndrome (PCOS) women were analyzed over a period of eighteen months from- May 2016 to October 2017. The study participants were divided into two groups as per 25(OH)D level. Those with 25(OH)D level <20 ng/ml (Vitamin D deficient) were taken group I and those having 25(OH)D level ≥ 20 ng/ml i.e., sufficient vitamin D levels were group II. We measured anthropometric measurements and metabolic parameters like lipid profile, fasting insulin, fasting blood sugars and HOMA-IR. Results: Eighty-five women were evaluated during the time period. The mean age of the study sample was 23.34 ± 4.587. Almost 40 % (n=34) of the study sample were vitamin D deficient and more than half of PCOS women (n=51) had sufficient vitamin D levels. Out of 85 women analyzed in this study, 48.23% were obese (Group I: 52.9% and 45.1% in group II). The vitamin D deficient group was comparable with the sufficient group in terms of anthropometric and biochemical parameters, except fasting serum insulin levels, which was infact lower in the vitamin D deficient group as compared to vitamin D sufficient group. None of the parameter showed any significant correlation with vitamin D. Conclusion: Hypovitaminosis is a common occurrence in PCOS women, necessitating the need for screening to prevent future adverse outcome. Further large-scale trials need to be done.