Phenotypic and Genotypic Shifts in Hepatitis B Virus in Treatment-Naive Patients, Taiwan, 2008–2012
oleh: Chau-Ting Yeh, Kung-Hao Liang, Ming-Ling Chang, Chao-Wei Hsu, Yi-Cheng Chen, Chih-Lang Lin, Wey-Ran Lin, Ming-Wei Lai
| Format: | Article |
|---|---|
| Diterbitkan: | Centers for Disease Control and Prevention 2017-05-01 |
Deskripsi
We examined the characteristic changes of hepatitis B virus (HBV) in antiviral drug treatment–naive patients referred for pretreatment evaluation in Taiwan during 2008–2012. Over time, we observed substantial decreases in the prevalence of HBV e antigen (HBeAg) and increasing prevalence of the precore G1899A mutation and HBV-DNA levels in HBeAg-positive patients.