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Medicine is an ever-changing science, and the pace of this change has been rapid in recent years. A researcher in an academic institution is now obliged to publish their research work for career advancement with recognition, access to grants, fellowships, etc., as secondary objectives. Besides, it is paramount for anyone engaging in active clinical practice to remain up to date with recent advances in the field. Hence, it is the author's responsibility to publish authentic data with integrity as it helps modulate opinions on a wide platform globally in today's digital age. While the pressure to publish is immense, it is vital to have a system of checks and balances before publishing and adhere to good research practices because a wrong step may bring lasting discredit to the authors. This article attempts to provide an overview for novice researchers regarding how to select an appropriate journal for publication, evaluate it in view of its reach and relevance, and how to avoid predatory journals. The article also briefly outlines the various databases available, peer-review process, important journal metrics such as impact factor and indexing, and the concept of open access in a simple language to enable young authors to select the best journal for publishing their work.