Time-programmable drug dosing allows the manipulation, suppression and reversal of antibiotic drug resistance in vitro
oleh: Mari Yoshida, Sabrina Galiñanes Reyes, Soichiro Tsuda, Takaaki Horinouchi, Chikara Furusawa, Leroy Cronin
| Format: | Article |
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| Diterbitkan: | Nature Portfolio 2017-06-01 |
Deskripsi
It is unclear whether strategies involving antibiotic cycling can efficiently control the emergence of antibiotic-resistant bacteria. Here, Yoshidaet al. show that the evolution of multi-drug-resistant bacteria in vitrocan be manipulated by administering pairs of antibiotics and switching between them.