Addition of Aripiprazole to the Clozapine May Be Useful in Reducing Anxiety in Treatment-Resistant Schizophrenia
oleh: Aleksandar Chanachev, Nicolas Ansermot, Séverine Crettol Wavre, Ute Nowotka, Maria-Eleni Stamatopoulou, Philippe Conus, Chin B. Eap
| Format: | Article |
|---|---|
| Diterbitkan: | Wiley 2011-01-01 |
Deskripsi
There exist many case reports and studies on the antipsychotic augmentation by aripirazole in partial responders to clozapine, the most seem to be finding a slight difference in the PANSS and CGI scores after the aripirazole addition. The results of our report are compatible with those of other studies but, we have found a considerable antianxiety action in both of the cases. The 5HT1A agonism of aripirazole could be hypothesized as mechanism contributing to this effect.