Flavin-enabled reductive and oxidative epoxide ring opening reactions

oleh: Bidhan Chandra De, Wenjun Zhang, Chunfang Yang, Attila Mándi, Chunshuai Huang, Liping Zhang, Wei Liu, Mark W. Ruszczycky, Yiguang Zhu, Ming Ma, Ghader Bashiri, Tibor Kurtán, Hung-wen Liu, Changsheng Zhang

Format: Article
Diterbitkan: Nature Portfolio 2022-08-01

Deskripsi

Epoxide ring opening reactions are important in both biological processes and synthetic applications. Here, the authors show that flavin cofactors can catalyze reductive and oxidative epoxide ring opening reactions and propose the underlying mechanisms.