Rapid transmission and tight bottlenecks constrain the evolution of highly transmissible SARS-CoV-2 variants
oleh: Emily E. Bendall, Amy P. Callear, Amy Getz, Kendra Goforth, Drew Edwards, Arnold S. Monto, Emily T. Martin, Adam S. Lauring
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2023-01-01 |
Deskripsi
Here, by sequencing viruses from individuals in multiple households, Bendall et al. find that SARS-CoV-2 transmission bottleneck does not vary between individuals infected with pre-variant lineages and those infected with highly transmissible Alpha, Delta, or Omicron variants, suggesting these tight bottlenecks will limit the spread of new mutations.