SARS-CoV-2 infection induces inflammatory bone loss in golden Syrian hamsters
oleh: Wei Qiao, Hui En Lau, Huizhi Xie, Vincent Kwok-Man Poon, Chris Chung-Sing Chan, Hin Chu, Shuofeng Yuan, Terrence Tsz-Tai Yuen, Kenn Ka-Heng Chik, Jessica Oi-Ling Tsang, Chris Chun-Yiu Chan, Jian-Piao Cai, Cuiting Luo, Kwok-Yong Yuen, Kenneth Man-Chee Cheung, Jasper Fuk-Woo Chan, Kelvin Wai-Kwok Yeung
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-05-01 |
Deskripsi
Although extrapulmonary complications of different organ systems are recognized in patients with severe COVID19 effects are less well studied. Here, Qiao et al. characterize the pathogenesis of SARS-CoV-2 on bone metabolism in Syrian hamster and find that bone loss is associated with virus-mediated cytokine dysregulation.