Phylogenetics and Pathogenesis of Early Avian Influenza Viruses (H5N1), Nigeria
oleh: Comfort O. Aiki-Raji, Patricia V. Aguilar, Yong-Kuk Kwon, Sue Goetz, David L. Suarez, Aashish I. Jethra, Oyekanmi Nash, Christopher A.O. Adeyefa, Festus D. Adu, David E. Swayne, Christopher F. Basler
| Format: | Article |
|---|---|
| Diterbitkan: | Centers for Disease Control and Prevention 2008-11-01 |
Deskripsi
Three highly pathogenic avian influenza subtype H5N1 and 4 Newcastle disease viruses were isolated from sick or dead chickens in southwestern Nigeria. Sequencing and phylogenetic analysis placed them within H5N1 subclade 2.2.2. Intravenous and intranasal pathogenicity tests produced systemic disease with vascular endothelial cell tropism in chickens.