The Antiallodynic Action of Pregabalin May Depend on the Suppression of Spinal Neuronal Hyperexcitability in Rats with Spared Nerve Injury
oleh: Lei Ding, Jie Cai, Xiang-Yang Guo, Xiu-Li Meng, Guo-Gang Xing
| Format: | Article |
|---|---|
| Diterbitkan: | Hindawi Limited 2014-01-01 |
Deskripsi
BACKGROUND: Pregabalin (PGB) is a novel antiepileptic drug and is also used as a first-line medication for the treatment of neuropathic pain. However, the mechanisms of its analgesic effects remain largely unknown.