Directing curli polymerization with DNA origami nucleators
oleh: Xiuhai Mao, Ke Li, Mengmeng Liu, Xinyu Wang, Tianxin Zhao, Bolin An, Mengkui Cui, Yingfeng Li, Jiahua Pu, Jiang Li, Lihua Wang, Timothy K. Lu, Chunhai Fan, Chao Zhong
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2019-03-01 |
Deskripsi
Curli are bacterial functional amyloids that have gained interest as self-assembling biomaterial for biotechnology applications. Here, the authors show that DNA origami decorated with CsgB nucleator proteins induced the site-specific nucleation and subsequent fibrillization of CsgA proteins.