An alternative synthesis of clindamycin
oleh: GRAHAM P. STEVENS, KEITH BOWDEN
| Format: | Article |
|---|---|
| Diterbitkan: | Serbian Chemical Society 2000-10-01 |
Deskripsi
A novel synthesis of clindamycin from lincomycin using N-chlorosuccinimide and triphenylphosphine is reported. This results in high yields and avoids the use of tetrachloromethane employed in the current manufacturing process.