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Catalytic enantioselective reductive domino alkyl arylation of acrylates via nickel/photoredox catalysis
oleh: Pengcheng Qian, Haixing Guan, Yan-En Wang, Qianqian Lu, Fan Zhang, Dan Xiong, Patrick J. Walsh, Jianyou Mao
Format: | Article |
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Diterbitkan: | Nature Portfolio 2021-11-01 |
Deskripsi
Enantioenriched α-aryl propionic acids are an important class of nonsteroidal anti-inflammatory medications. Here the authors use a visible-light-promoted photoredox/nickel catalyzed method to form such compunds via a three-component alkyl arylation of acrylates.