Regulatory protein HilD stimulates Salmonella Typhimurium invasiveness by promoting smooth swimming via the methyl-accepting chemotaxis protein McpC
oleh: Kendal G. Cooper, Audrey Chong, Laszlo Kari, Brendan Jeffrey, Tregei Starr, Craig Martens, Molly McClurg, Victoria R. Posada, Richard C. Laughlin, Canaan Whitfield-Cargile, L. Garry Adams, Laura K. Bryan, Sara V. Little, Mary Krath, Sara D. Lawhon, Olivia Steele-Mortimer
| Format: | Article |
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| Diterbitkan: | Nature Portfolio 2021-01-01 |
Deskripsi
Protein HilD of Salmonella Typhimurium coordinates motility and host cell invasion by upregulating flagellar genes and a secretion system. Here, Cooper et al. show that HilD also modulates swimming behaviour by upregulating a subunit of the chemotactic receptor array, and this is important for invasion of epithelial cells.