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Multidrug resistant (MDR) <i>Salmonella</i> are a leading cause of foodborne diseases and serious human health concerns worldwide. In this study we detected MDR <i>Salmonella</i> in broiler chicken along with the resistance genes and class 1 integron gene <i>intl1</i>. A total of 100 samples were collected from broiler farms comprising 50 cloacal swabs, 35 litter and 15 feed samples. Overall prevalence of <i>Salmonella</i> was 35% with the highest detected in cloacal swabs. Among the <i>Salmonella</i>, 30 isolates were confirmed as <i>S. enterica</i> serovar Typhimurium using molecular methods of PCR. Disk diffusion susceptibility test revealed that all the <i>Salmonella</i> were classified as MDR with the highest resistance to tetracycline (97.14%), chloramphenicol (94.28%), ampicillin (82.85%) and streptomycin (77.14%). The most prevalent resistance genotypes were <i>tetA</i> (97.14%), <i>floR</i> (94.28%), <i>bla_TEM-1</i> (82.85%) and <i>aadA1</i> (77.14%). In addition, among the MDR <i>Salmonella,</i> 20% were positive for class 1 integron gene (<i>intl1)</i>. As far as we know, this is the first study describing the molecular basis of antibiotic resistance in MDR <i>Salmonella</i> from broiler farms in Bangladesh. In addition to <i>tetA, floR, bla_TEM-1</i>, <i>aadA1</i> and <i>intl1</i> were also detected in the isolated MDR <i>Salmonella.</i> The detection of MDR <i>Salmonella</i> in broiler chicken carrying <i>intl1</i> is of serious public health concern because of their zoonotic nature and possibilities to enter into the food chain.