Evaluation of 3′-phosphate as a transient protecting group for controlled enzymatic synthesis of DNA and XNA oligonucleotides
oleh: Marie Flamme, Steven Hanlon, Irene Marzuoli, Kurt Püntener, Filippo Sladojevich, Marcel Hollenstein
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-06-01 |
Deskripsi
Controlled enzymatic DNA synthesis represents an alternative synthetic methodology that circumvents the limitations of traditional soild-phase synthesis. Here, the authors explore the use of 3’-phosphate as a transient protecting group for the controlled enzymatic synthesis of DNA and XNA oligonucleotides.