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We study the transport properties of generic out-of-equilibrium quantum systems connected to fermionic reservoirs. We develop a perturbation scheme in the inverse system size, named 1/N expansion, to study a large class of out of equilibrium diffusive/ohmic systems. The bare theory is described by a Gaussian action corresponding to a set of independent two level systems at equilibrium. This allows a simple and compact derivation of the diffusive current as a first-order pertubative term. In addition, we obtain exact solutions for a large class of quantum stochastic Hamiltonians (QSHs) with time and space dependent noise, using a self-consistent Born diagrammatic method in the Keldysh representation. We show that these QSHs exhibit diffusive regimes, which are encoded in the Keldysh component of the single particle Green's function. The exact solution for these QSHs models confirms the validity of our system size expansion ansatz, and its efficiency in capturing the transport properties. We consider in particular three fermionic models: (i) a model with local dephasing, (ii) the quantum simple symmetric exclusion process model, and (iii) a model with long-range stochastic hopping. For (i) and (ii) we compute the full temperature and dephasing dependence of the conductance of the system, both for two- and four-points measurements. Our solution gives access to the regime of finite temperature of the reservoirs, which could not be obtained by previous approaches. For (iii), we unveil a ballistic-to-diffusive transition governed by the range and the nature (quantum or classical) of the hopping. As a byproduct, our approach equally describes the mean behavior of quantum systems under continuous measurement.