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Gas-Phase Fragmentation of Cyclic Oligosaccharides in Tandem Mass Spectrometry
oleh: Alexander O. Chizhov, Yury E. Tsvetkov, Nikolay E. Nifantiev
Format: | Article |
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Diterbitkan: | MDPI AG 2019-06-01 |
Deskripsi
Modern mass spectrometry, including electrospray and MALDI, is applied for analysis and structure elucidation of carbohydrates. Cyclic oligosaccharides isolated from different sources (bacteria and plants) have been known for decades and some of them (cyclodextrins and their derivatives) are widely used in drug design, as food additives, in the construction of nanomaterials, etc. The peculiarities of the first- and second-order mass spectra of cyclic oligosaccharides (natural, synthetic and their derivatives and modifications: cyclodextrins, cycloglucans, cyclofructans, cyclooligoglucosamines, etc.) are discussed in this minireview.