Laser-Synthesized SERS Substrates as Sensors toward Therapeutic Drug Monitoring

oleh: Matteo Tommasini, Chiara Zanchi, Andrea Lucotti, Alessandro Bombelli, Nicolò S. Villa, Marina Casazza, Emilio Ciusani, Ugo de Grazia, Marco Santoro, Enza Fazio, Fortunato Neri, Sebastiano Trusso, Paolo M. Ossi

Format: Article
Diterbitkan: MDPI AG 2019-05-01

Deskripsi

The synthesis by pulsed laser ablation and the characterization of both the surface nanostructure and the optical properties of noble metal nanoparticle-based substrates used in Surface Enhanced Raman Spectroscopy are discussed with reference to application in the detection of anti-epileptic drugs. Results on two representative drugs, namely Carbamazepine and Perampanel, are critically addressed.