Solvent-free synthesis of α-aminophosphonates: Cellulose-SO3H as an efficient catalyst

oleh: Krishnammagari Suresh Kumar, Balam Satheesh Krishna, Chinnapareddy Bhupendra Reddy, Mudumala Veera Narayana Reddy, Cirandur Suresh Reddy

Format: Article
Diterbitkan: Elsevier 2017-02-01

Deskripsi

α-Aminophosphonates possess a broad range of applications ranging from agrochemistry to medicine. We developed an efficient and eco-friendly Cellulose-SO3H catalyzed one-pot synthesis of α-aminophosphonates by three-component, room temperature reaction of an aldehyde, an amine and dialkylphosphite under solvent-free conditions. The major advantages of the present method are simple experimentation, use of inexpensive and eco-friendly reusable catalyst with good yields and short reaction times.