Adenoviromics: Mining the Human Adenovirus Species D Genome

oleh: Ashrafali M. Ismail, Ji Sun Lee, Jeong Yoon Lee, Jeong Yoon Lee, Gurdeep Singh, Gurdeep Singh, David W. Dyer, Donald Seto, James Chodosh, Jaya Rajaiya

Format: Article
Diterbitkan: Frontiers Media S.A. 2018-09-01

Deskripsi

Human adenovirus (HAdV) infections cause disease world-wide. Whole genome sequencing has now distinguished 90 distinct genotypes in 7 species (A-G). Over half of these 90 HAdVs fall within species D, with essentially all of the HAdV-D whole genome sequences generated in the last decade. Herein, we describe recent new findings made possible by mining of this expanded genome database, and propose future directions to elucidate new functional elements and new functions for previously known viral components.