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Incorporating cost-effectiveness data in the priority-setting decisions is a distinguishing feature in the Swedish national guidelines. This differentiates the Swedish guidelines from its European and American counterparts. The broader perspective is aimed at facilitating explicit resource allocations and priority-setting in healthcare, all in accordance with the three guiding ethical principles stated in the Health and Medical Services Act.1 The guidelines consist of recommendations in the form of a priority-setting decisions produced by a Priority-Setting Group (PSG) and the work process involves appraising the evidence used as decision support (including cost-effectiveness).