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Microwave-Assisted Synthesis of Some Potential Bioactive Imidazolium-Based Room-Temperature Ionic Liquids
oleh: Ahmed H. Albalawi, Wael S. El-Sayed, Ateyatallah Aljuhani, Saud M. Almutairi, Nadjet Rezki, Mohamed R. Aouad, Mouslim Messali
Format: | Article |
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Diterbitkan: | MDPI AG 2018-07-01 |
Deskripsi
An environmentally-friendly and easy synthesis of a series of novel functionalized imidazolium-based ionic liquids (ILs) is described under both the conventional procedure and microwave irradiation. The structures of newly synthesized room-temperature ionic liquids (RTILs) were established by different spectral analyses. All ILs (1–14) were screened for their in vitro antimicrobial activity against a panel of clinically isolated bacteria. The results of the minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC) showed that some of the tested ILs are very promising anti-bacterial agents especially those containing an alkyl chain with a phenyl group (most notably 1, 2, 12, and 13).