DHX9 helicase promotes R-loop formation in cells with impaired RNA splicing

oleh: Prasun Chakraborty, Jeffrey T. J. Huang, Kevin Hiom

Format: Article
Diterbitkan: Nature Portfolio 2018-10-01

Deskripsi

Unresolved R-loops can represent a threat to genome stability. Here the authors reveal that DHX9 helicase can promote R-loop formation in the absence of splicing factors SFPQ and SF3B3.