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The innovative resource of SMEs themselves is very limited, resulting in low technological innovation capability. The reasons of low technological innovation capability were analyzed. In addition, the mechanism of improving the technological innovation capability of SMEs by University-Industry collaboration was explored from several following sides: enhancing enterprise learning capacity, speeding up the flow of information, the internalization of external talents, realizing the innovation resource sharing and so on. The conclusion of this paper has great significance to UniversityIndustry Collaboration and enhances their innovation capability