Reconstruction and topological characterization of the sigma factor regulatory network of Mycobacterium tuberculosis
oleh: Rinki Chauhan, Janani Ravi, Pratik Datta, Tianlong Chen, Dirk Schnappinger, Kevin E. Bassler, Gábor Balázsi, Maria Laura Gennaro
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2016-03-01 |
Deskripsi
Sigma factors are regulatory proteins that reprogram the bacterial RNA polymerase in response to stress conditions to transcribe certain genes, including those for other sigma factors. Here, Chauhan et al. describe the complete sigma factor regulatory network of the pathogen Mycobacterium tuberculosis.