Structural basis of ECF-σ-factor-dependent transcription initiation
oleh: Wei Lin, Sukhendu Mandal, David Degen, Min Sung Cho, Yu Feng, Kalyan Das, Richard H. Ebright
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2019-02-01 |
Deskripsi
No structural data have been available for RNA polymerase holoenzymes or transcription initiation complexes that contain extracytoplasmic σ factors. Here the authors report the crystal structures of transcription initiation complexes comprising Mycobacterium tuberculosis RNA polymerase, extracytoplasmic σ factor σL and promoter DNA.