Transiently antigen-primed B cells return to naive-like state in absence of T-cell help

oleh: Jackson S. Turner, Matangi Marthi, Zachary L. Benet, Irina Grigorova

Format: Article
Diterbitkan: Nature Portfolio 2017-04-01

Deskripsi

B-cell encounter with antigen is thought to result in anergy, cell death, or a productive B-cell response. Here the authors show that transient antigen acquisition can enable B-cell recruitment into productive responses or a return to a naive-like state, depending on availability of T-cell help.