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Persistent activation of central amygdala CRF neurons helps drive the immediate fear extinction deficit
oleh: Yong S. Jo, Vijay Mohan K. Namboodiri, Garret D. Stuber, Larry S. Zweifel
Format: | Article |
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Diterbitkan: | Nature Portfolio 2020-01-01 |
Deskripsi
Learned conditioned fear associations can be weakened (extinction learning), but extinction is less effective if performed too soon after the original fear conditioning. Here, the authors show that persistent activation of CRF-expressing neurons in the central amygdala is involved in the early fear extinction deficit.