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Single molecule multiplexed nanopore protein screening in human serum using aptamer modified DNA carriers
oleh: Jasmine Y. Y. Sze, Aleksandar P. Ivanov, Anthony E. G. Cass, Joshua B. Edel
Format: | Article |
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Diterbitkan: | Nature Portfolio 2017-11-01 |
Deskripsi
It is still a challenge for current nanopore sensing methods to differentiate multiple analytes from complex biological material. Here, the authors graft nucleic acid aptamer sequences along the backbone of a double stranded DNA carrier for the detection of multiple protein targets in human serum.