Single molecule multiplexed nanopore protein screening in human serum using aptamer modified DNA carriers

oleh: Jasmine Y. Y. Sze, Aleksandar P. Ivanov, Anthony E. G. Cass, Joshua B. Edel

Format: Article
Diterbitkan: Nature Portfolio 2017-11-01

Deskripsi

It is still a challenge for current nanopore sensing methods to differentiate multiple analytes from complex biological material. Here, the authors graft nucleic acid aptamer sequences along the backbone of a double stranded DNA carrier for the detection of multiple protein targets in human serum.