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Case report: We present the clinical picture and laboratory work-up of Glanzmann thrombasthenia, based on a group of 7 patients. Bleeding history was significant in all patients and included both mucosal and postsurgery bleeds. Laboratory analysis revealed decreased or absent platelet aggregation (< 10%) with all physiologic agonists (ADP, collagen, epinephrin, arachidonic acid) together with normal agglutination response to ristocetin. In three patients diagnosis was confirmed by flow cytometry.