AIP1 and cofilin ensure a resistance to tissue tension and promote directional cell rearrangement
oleh: Keisuke Ikawa, Kaoru Sugimura
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2018-09-01 |
Deskripsi
Cells must resist or release tension/compression when proliferating and moving during development. Here the authors show that AIP1, together with cofilin, promotes local actin turnover to regulate linkage between actomyosin and cell junctions and resist mechanical load imposed by tissue stretching.