Evaluation of genetic markers linked to hemophilia A locus: an Indian experience
oleh: Atreyee Saha, Saibal Mukherjee, Mahua Maulik, Giriraj Ratan Chandak, The Indian Genome Variation Consortium, Kunal Ray
| Format: | Article |
|---|---|
| Diterbitkan: | Ferrata Storti Foundation 2007-12-01 |
Deskripsi
Hemophilia A is an X-linked recessive bleeding disorder caused by defects in factor VIII gene (F8). Our study examines variations of single nucleotide polymorphism (SNP) in F8 in the Indian population and establishes the utility of a combination of SNP and microsatellite markers for the successful identification of carriers in the affected families.