Find in Library
Search millions of books, articles, and more
Indexed Open Access Databases
Multifunctional Plant Virus Nanoparticles for Targeting Breast Cancer Tumors
oleh: Mehdi Shahgolzari, Hassan Dianat-Moghadam, Afagh Yavari, Steven N. Fiering, Kathleen Hefferon
Format: | Article |
---|---|
Diterbitkan: | MDPI AG 2022-08-01 |
Deskripsi
Breast cancer treatment using plant-virus-based nanoparticles (PVNPs) has achieved considerable success in preclinical studies. PVNP-based breast cancer therapies include non-targeted and targeted nanoplatforms for delivery of anticancer therapeutic chemo and immune agents and cancer vaccines for activation of local and systemic antitumor immunity. Interestingly, PVNP platforms combined with other tumor immunotherapeutic options and other modalities of oncotherapy can improve tumor efficacy treatment. These applications can be achieved by encapsulation of a wide range of active ingredients and conjugating ligands for targeting immune and tumor cells. This review presents the current breast cancer treatments based on PVNP platforms.